En passant: After the war, John Cade was made director of the Bundoora Repatriation Mental Hospital and moved his family into a house of the asylum grounds. The two hundred patients there included many manic-depressives and John became preoccupied by the “absolute failure” of psychotherapy to cure them. “Psychopathological explanations seemed to me to be singularly unconvincing,” he reflected, “and completely useless when it came to treatment or prevention of attacks.” He wanted to know the “essential nature” of the disease, and like many naturalists and herbalists and folk healers before him, he knew that the malady must come from some imbalance in the harmony of the body, in excesses or deficits or toxins.
In 1969: Forty-nine countries had approved the use of lithium, but the United States was not among them. Many years later, Cade himself would write that his cure was “made by an unknown psychiatrist, working alone in a small chronic hospital with no research training, primitive techniques, and negligible equipment.” Who could expect the Americans to care? In many official histories, American skepticism has been attributed to the lithia craze, to wariness around the substance in the decades after lithium had left so many Americans dead. But those with experience in natural remedies know the truth: the trouble was money. Lithium is found in water, in rocks, in soil, in the sea. It cannot be placed under patent. It has no commercial value. Even today, it can be made by pharmacists in-house, without the trade secrets of pharmaceutical conglomerates, without the true incentives of modern medicine.

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